Bulk L-Glutamine — Free-Form & Peptide-Bonded Grades for OEM/ODM | Aidacru
Aidacru supplies bulk L-Glutamine in two B2B production grades — Free-Form L-Glutamine (the conventional crystalline powder, the most-abundant amino acid in human skeletal muscle and plasma) and L-Alanyl-L-Glutamine (a stabilized dipeptide form with significantly higher aqueous solubility and pH stability, increasingly specified in ready-to-drink, intra-workout, and clinical nutrition formats).
Both grades are produced via microbial fermentation of plant-sourced (non-GMO corn or sugarcane) glucose substrate — no animal-derived, no human-hair, no duck-feather origin — and are HPLC-assayed against USP, EP, and JP pharmacopoeial standards. L-Glutamine has been studied for its role in protein metabolism, gut-barrier function, and post-exercise recovery, and is used as a raw material in sports nutrition, clinical/medical nutrition, gut-health formulas, recovery blends, and amino acid stacks.
Each batch ships with full COA (HPLC assay), residual solvents profile, heavy metals, microbiological testing, and source verification statement. Packaging in 25 kg fiber drums with double food-grade PE liner.
- Product Details
- Technical Specification
- After-sale service
Aidacru's bulk L-Glutamine is supplied as a raw material to international B2B clients — including sports nutrition brands, contract manufacturers, clinical/medical nutrition formulators, gut-health brands, and OEM/ODM private-label houses. Both grades are produced through microbial fermentation of plant-sourced (non-GMO corn or sugarcane) glucose substrate under GMP conditions, then purified to pharmacopoeial specification. The material is supplied strictly as a raw ingredient for further formulation; it is not sold as a finished consumer dosage form.
Raw Material Features:
Two production grades: Free-Form L-Glutamine (USP/EP/JP) and L-Alanyl-L-Glutamine peptide
Fermented from plant-source glucose — no animal-derived, no human-hair, no duck-feather origin
Peptide grade offers ~10× the aqueous solubility and superior pH/heat stability vs. free L-Glutamine
Vegan, Halal-certifiable, Kosher-certifiable, Non-GMO, Allergen-free
HPLC-assayed against USP / EP / JP monographs (Free-Form grade)
Each batch ships with full COA + HPLC assay + source verification statement
These statements have not been evaluated by the Food and Drug Administration. This raw material is not intended to diagnose, treat, cure, or prevent any disease.
| Specification | Free-Form L-Glutamine | L-Alanyl-L-Glutamine (Peptide-Bonded) |
| Product Name | L-Glutamine, Fermented | L-Alanyl-L-Glutamine, Fermented |
| CAS Number | 56-85-9 | 39537-23-0 |
| Molecular Formula | C₅H₁₀N₂O₃ | C₈H₁₅N₃O₄ |
| Molecular Weight | 146.14 | 217.22 |
| Source | Plant-based microbial fermentation (Non-GMO corn / sugarcane glucose) | Plant-based microbial fermentation + enzymatic peptide synthesis |
| Form | Crystalline powder | Fine powder |
| Appearance | White to off-white crystalline powder | White to off-white fine powder |
| Assay (HPLC, anhydrous basis) | ≥ 99.0% (per USP/EP/JP) | ≥ 98.0% |
| Free L-Glutamine in Peptide | N/A | ≤ 1.0% |
| Free L-Alanine in Peptide | N/A | ≤ 1.0% |
| Aqueous Solubility (20 °C) | ~ 36 g/L | ~ 568 g/L (≈ 15× higher) |
| Stability in Solution | Degrades under heat / acid / extended storage → forms pyroglutamate + ammonia | High stability in solution, retort, and across wide pH range |
| Specific Rotation | +6.3° to +7.3° (per USP) | +5.5° to +7.5° |
| Particle Size | 95% pass 60 mesh | 95% pass 60 mesh |
| Loss on Drying | ≤ 0.5% | ≤ 1.0% |
| Residue on Ignition | ≤ 0.1% | ≤ 0.2% |
| Residual Solvents | Meets ICH Q3C limits | Meets ICH Q3C limits |
| Heavy Metals | Pb ≤ 0.5 ppm / As ≤ 0.5 ppm / Cd ≤ 0.5 ppm / Hg ≤ 0.1 ppm | Same |
| Microbiological | TPC ≤ 1,000 cfu/g; Yeast & Mold ≤ 100 cfu/g; E. coli / Salmonella Negative | Same |
| Pharmacopoeial Compliance | USP / EP / JP | In-house spec (peptide-grade, no monograph) |
| Shelf Life | 36 months (sealed, cool, dry) | 36 months (sealed, cool, dry) |
| Packaging | 25 kg fiber drum with double food-grade PE liner | 25 kg fiber drum with double food-grade PE liner |
| Testing Methods | HPLC (assay), ICP-MS (heavy metals), GC (residual solvents) | HPLC (peptide + free-AA profile), ICP-MS, GC |
| Certifications | GMP, ISO 22000, HALAL, KOSHER (optional), Non-GMO Project verifiable, Vegan-certifiable | Same |
| Best Application | Capsules, tablets, dry powder blends, sticks (consumed immediately after mixing) | RTD beverages, retort-processed liquids, clinical nutrition, intra-workout drinks, wide-pH formulas |
| Origin | Guangzhou, China (fermentation-sourced from qualified GMP partner facilities) | Same |
Minimum Order & Pricing
MOQ: 5 kg for sample / formulation trial; standard production orders from 25 kg (single fiber drum)
Trial samples of 100 g – 500 g available with full COA
Tiered B2B pricing for 25 kg / 100 kg / 500 kg / 1 MT / FCL volumes
FOB Guangzhou; CIF/DDP available to most major ports (US, EU, MENA, LatAm, SE Asia)
Spot-stock available for Free-Form L-Glutamine; Peptide grade typically 10–21 day lead time
Quality Assurance
Manufactured / sourced from GMP-certified, FDA-registered facilities with ISO 22000 food-safety system
Raw material from qualified fermentation partners with documented non-animal, non-hair, non-feather origin
Every batch tested for assay (HPLC), residual solvents (GC, ICH Q3C), heavy metals (ICP-MS), microbiological load, and (for peptide grade) free-AA profile
Pharmacopoeial compliance (USP / EP / JP) verified for Free-Form grade per monograph
COA, MSDS, Allergen Statement, Non-GMO Statement, Vegan Statement, Source Origin Declaration, HALAL & KOSHER certificates provided
Retention samples held for 36 months
Third-party verification (Eurofins / SGS / Intertek) supported on request
Technical Support
Grade selection consulting — Free-Form vs Peptide based on dosage form, processing conditions, and target market:
Dry powders & capsules → Free-Form is cost-effective and pharmacopoeial-compliant
Liquid / RTD / retort / wide-pH formulas → L-Alanyl-L-Glutamine for solubility and stability
Stack formulation support for L-Glutamine + BCAA / EAA, L-Glutamine + Citrulline, L-Glutamine + Electrolyte recovery blends, and gut-health stacks (L-Glutamine + Zinc Carnosine + Aloe extract)
Stability and shelf-life testing support for liquid applications using the peptide grade
Particle-size and bulk-density customization for capsule fill optimization
Private-label and OEM/ODM finished-product manufacturing also available (capsules, tablets, single-serve sticks, tubs, RTD)
Stability data sheets and packaging compatibility guidance provided
